When allergies or anxiety takes over your pet, you know how hard it is to watch them go through that pain. However, there is a solution: Benadryl for dogs. Doctors give trusted answers on uses, effects, side-effects, and cautions: Dr. Khanna on benadryl zyrtec interaction: May not be a good idea. What are your symptoms sometimes a doctor may add steroids and other instructions to control severe allergic Rhinitis Benadryl is an over-the-counter medicine that can be given to dogs. Diphenhydramine, the most common active ingredient, is an H 1 antagonist, which means it helps to prevent the uptake of histamine (a type of substance responsible for allergic reactions) by receptors in the body. Always consider a professional before giving your dog Benadryl. You can use this table as an instrument to see how much Benadryl (Diphenhydramine) you can give your dog. Original review: April 13, 2018. Benadryl Allergy Liquidgels - I am very upset I purchased this product at a Dollar General Store (I have since called and spoke with them didn't help much). Hello! For the past month I have had random hives appear all over my body. And I mean random, I go days without having one single hive and then all of a sudden patches of hives appear! Can you Give Dogs Benadryl Made for Human Consumption? There are currently no products of this nature made specifically for dogs, so if your vet does recommend it, the medication made for humans is the only available ‘over the counter’ option. Be careful when you choose the medicine. Some brands of diphenhydramine are packaged to look like Benadryl (same colors, etc.) but contain ingredients that can be very harmful and often fatal to dogs. Hello, Hives result from dilation of capillaries allowing fluid to leak out into the surrounding tissue, the epidermis.They are red, itchy, raised areas of skin that appear in varying shapes and sizes. Questions & Answers. 1. Can you give a dog Benadryl? Yes! Dogs can take Benadryl, for much the same purposes as humans. On the other hand, the dosage is different for dogs, or even a dog the same size.